Mercedes E350 owners know that a smooth engine depends on clean oil and a reliable filter. The right oil filter traps dirt, metal particles, and sludge before they can harm vital engine parts. A poor filter can reduce oil flow, speed up wear, and shorten engine life, which makes smart filter selection essential for long-term performance.
This guide covers five of the best oil filters for Mercedes E350 models, focusing on build quality, filtration efficiency, fitment accuracy, and value. Each option helps protect your engine during daily commutes, highway drives, and long service intervals.
Premium materials, durable seals, and OEM-level design all play a major role in keeping your luxury sedan running at its best. You will also find filters that support steady oil pressure and help maintain fuel efficiency. A solid pick today can save you from costly engine repairs later and keep your E350 performing smoothly for years.
5 Best Oil Filters for Mercedes E350
Our Top 5 Best Oil Filters For Mercedes E350 Reviews – Expert Tested & Recommended
1. Mercedes-Benz Oil Filter 2-Pack – Replaces 2761800009
This genuine-style 2-pack oil filter is built specifically for a wide range of Mercedes-Benz models, including the E350, and replaces OE part number 2761800009. Designed to meet or exceed OEM standards, it delivers reliable engine protection with easy installation and included O-rings for a complete seal.
Key Features That Stand Out
- ✓ Direct replacement for OE part 2761800009
- ✓ Compatible with C350, E350, CLS550, ML350, and more
- ✓ Includes high-quality O-rings for leak-free installation
- ✓ Made from durable materials that meet OEM specifications
Why We Recommend It
As our top pick, this filter offers factory-grade performance at an excellent value. The inclusion of O-rings and precise fitment makes it ideal for DIYers who want peace of mind without paying dealership prices.
Best For
Owners of E350 models from 2007–2016 looking for an affordable yet reliable OEM-equivalent filter with proven compatibility.
Pros and Cons
Pros:
- Exact fit for multiple Mercedes platforms
- Includes all necessary gaskets and seals
- Cost-effective 2-pack for future changes
- Meets or exceeds original equipment standards
Cons:
- Not branded as “genuine Mercedes” (though functionally identical)
- Limited availability in some regions
Customer Reviews
“Great value for a high quality filter. O-rings included for easy replacement. Exact fit and works great.” – Customer Review
“These filters are top quality for my 2015 Audi S5 convertible, they meet OEM spec and are very easy to install. They come with all O-rings in the box, and they are designed to fit the Audi V6 supercharged engine. The price is a bargain because you get two filters for less than what one of the other…” – Customer Review
2. Mann HU 7025z Oil Filter – OEM Replacement
The Mann HU 7025z is a premium OEM-grade filter trusted by European automakers. Engineered for high-performance engines like those in the E350, it provides superior filtration, consistent oil flow, and long-lasting seal integrity thanks to precision-molded end caps and flexible O-rings.
Key Features That Stand Out
- ✓ Original equipment supplier for Mercedes-Benz
- ✓ Advanced cellulose media captures microscopic contaminants
- ✓ Reinforced steel casing resists pressure and corrosion
- ✓ Flexible NBR O-ring ensures leak-free operation
Why We Recommend It
Mann is a name synonymous with German engineering excellence. This filter delivers OE-level performance and reliability, making it the go-to choice for enthusiasts and professionals who demand the best.
Best For
Mercedes E350 owners who prioritize OEM quality, especially those with turbocharged or high-mileage engines needing top-tier protection.
Pros and Cons
Pros:
- Proven track record with European luxury brands
- Exceptional build quality and material durability
- Consistent performance across temperature ranges
- Widely used in dealership service centers
Cons:
- Slightly higher price than aftermarket alternatives
- Some users note visible seam on filter body (normal in manufacturing)
Customer Reviews
“Clean and solid install. No Oring issue. Good price. Don’t really need to say more. If you’re doing the oil change yourself and want a good quality part without breaking the bank, buy it.” – Customer Review
“I ordered these and the ones I received are genuine. MANN filters are really excellent. Some people complain about the seam in the filter. It’s how the filter is made and not a defect at all. When you do an oil change it’s good practice to cut the filter open and check for the trapped debris. Cut t…” – Customer Review
3. K&N Select SO-7004 Oil Filter – Engine Protection & Performance
K&N brings its racing heritage to the SO-7004 filter, offering up to 20,000 miles of engine protection with 99% filtration efficiency. Designed for synthetic and conventional oils, it’s a versatile, high-value option for E350 owners who want performance without premium pricing.
Key Features That Stand Out
- ✓ Captures 99% of contaminants over 30 microns
- ✓ Compatible with all oil types (synthetic, conventional, blends)
- ✓ Long-life design supports extended drain intervals
- ✓ Durable canister construction with anti-drainback valve
Why We Recommend It
K&N combines affordability with impressive specs, making this filter ideal for budget-conscious drivers who still want strong engine protection and brand credibility.
Best For
DIY mechanics and cost-aware E350 owners using synthetic or high-mileage oil who want reliable filtration at a lower price point.
Pros and Cons
Pros:
- Excellent filtration efficiency for the price
- Works with all common motor oil formulations
- Easy to install with standard tools
- Backed by K&N’s reputation in performance filtration
Cons:
- Not an OEM-spec part (may not satisfy purists)
- Shorter track record in Mercedes applications vs. Mann or Bosch
Customer Reviews
“easy to install, works great, good value” – Customer Review
4. HU821X Oil Filter 24-Pack – Replaces 6421800009 & More
This bulk 24-pack of HU821X filters offers incredible value for fleet owners, shops, or multi-car households. Designed for diesel and gasoline Mercedes models (including Sprinter and E350 variants), it replaces several OE numbers and delivers consistent filtration across diverse applications.
Key Features That Stand Out
- ✓ Replaces HU821X, 6421800009, 72263WS, and more
- ✓ Fits V6 3.0L diesel and gasoline engines
- ✓ High-capacity media for extended service life
- ✓ Economical per-unit cost in bulk packaging
Why We Recommend It
If you own multiple Mercedes vehicles or run a small shop, this pack delivers unmatched value without sacrificing core filtration performance.
Best For
Commercial users, multi-vehicle families, or anyone performing frequent oil changes who needs a cost-effective, compatible filter solution.
Pros and Cons
Pros:
- Extremely low cost per filter
- Broad compatibility across Mercedes and Freightliner platforms
- Reliable basic filtration for standard driving conditions
Cons:
- Overkill for single-vehicle owners
- Generic branding lacks OE cachet
- May not meet strict OEM tolerances for high-performance use
5. Mercedes-Benz Oil Filter HU7025z – Replaces Mann HU7025z & 2761800009
This aftermarket filter cross-references both Mann HU7025z and Mercedes OE number 2761800009, offering broad compatibility with E350, ML350, C300, and S550 models. It includes a high-quality O-ring and is built to handle normal and high-mileage driving conditions.
Key Features That Stand Out
- ✓ Interchanges with HU7025Z and 2761800009
- ✓ Includes replacement O-ring for complete install
- ✓ Tested for environmental durability and material stability
- ✓ Suitable for 5,000–7,500 mile change intervals
Why We Recommend It
A solid alternative for E350 owners who want cross-compatibility and reliable performance without paying OEM premiums. Great for those who rotate between multiple Mercedes models.
Best For
Owners of multiple Mercedes vehicles (E350, C300, ML350) seeking a universal filter solution with verified fitment.
Pros and Cons
Pros:
- Cross-compatible with several popular Mercedes filters
- Includes all necessary installation hardware
- Affordable price with decent build quality
- Positive long-term user feedback
Cons:
- Not a household brand name like Mann or Bosch
- Filtration media may not match premium OE density
Customer Reviews
“I have bought this filter many many times with zero issues. Quality is what it should be and easy to install.” – Customer Review
“Fits great in my daughter GLK 350 Mercedes” – Customer Review
Complete Buying Guide for Best Oil Filters for Mercedes E350
Essential Factors We Consider
When selecting the best oil filter for your Mercedes E350, we evaluate fitment accuracy, filtration efficiency, material quality, and real-world reliability. The E350’s M276 V6 engine demands a filter that maintains consistent oil pressure, resists collapse under load, and traps fine particles without restricting flow.
We also prioritize filters that include proper O-rings or gaskets—leaks during oil changes are frustrating and messy. Finally, we consider value: whether you’re paying for genuine Mercedes branding or getting comparable performance from a trusted aftermarket brand like Mann or K&N.
Budget Planning
Oil filters for the E350 range from under $10 to over $25 per unit. While OEM filters offer peace of mind, high-quality aftermarket options like the Mann HU 7025z deliver nearly identical performance at a lower cost.
For most owners, spending $12–$18 per filter strikes the right balance between quality and economy. Buying in multi-packs (like the 2-pack or 24-pack options) can further reduce long-term costs especially if you perform your own maintenance.
Final Thoughts
Your Mercedes E350 deserves a filter that protects its engineering excellence. Whether you choose our Best Choice (Mercedes-Benz 2-Pack), the Editor’s Choice (Mann HU 7025z), or the Best Budget pick (K&N SO-7004), you’re investing in smoother operation, cleaner oil, and fewer engine worries down the road.
Frequently Asked Questions
Q: What oil filter fits a Mercedes E350?
A: The most common compatible filters include part numbers 2761800009 and HU7025z. Always verify your model year and engine type before purchasing, as some E350 variants (especially diesel or AMG trims) may require different filters.
Q: Can I use an aftermarket oil filter on my Mercedes E350?
A: Yes, many aftermarket filters (like those from Mann, K&N, or Bosch) meet or exceed OEM specifications. Just ensure they’re listed as compatible with your specific E350 model and include proper sealing components.
Q: How often should I change the oil filter in my E350?
A: Mercedes typically recommends changing the oil and filter every 10,000 miles or 12 months, whichever comes first especially if using synthetic oil. For severe driving conditions (frequent short trips, towing, extreme temperatures), consider changing it every 5,000–7,500 miles.
Q: Does the oil filter affect engine performance?
A: Indirectly, yes. A clogged or low-quality filter can restrict oil flow, reduce lubrication, and increase engine wear. A properly functioning filter ensures clean oil circulates efficiently, supporting optimal performance and longevity.
Q: Should I buy a genuine Mercedes oil filter?
A: Genuine filters offer guaranteed compatibility and quality, but reputable aftermarket brands often provide similar performance at a lower price. For most E350 owners, a high-quality aftermarket filter is a smart, cost-effective choice.